I always love these, so creepy. As always, the little details are what make it. I really liked that quick change in scenery when the fire alarm goes off, as though you see the world through Skitzo's perspective where everything is alright until his eyes go red and its a scene of dischord. The music slowing there was a great touch. The only way I could see this being better would be to keep the black screen and silence at the end instead of looping it to the preloader screen (not sure if that's possible with flash though). The extended pause of it at the end gave a sense of despair and hopelessness which only helped the overall creepiness of it (another great touch), but waiting for the preloader screen and have it never come...it just seems so dark and final.
Anyway, as a series, I like how it keeps to its dark theme (I think we all have an idea of how it's gonna end) as well as being a 1920's cartoon. The mix is such a juxtaposition and I love it every time! Keep up the great work!